drbubb Posted December 6, 2012 Report Share Posted December 6, 2012 Rejuvenation : Is it possible? Strategies & techniques Wiki definition : is the hypothetical reversal of the aging process. Rejuvenation is distinct from life extension. Life extension strategies often study the causes of aging and try to oppose those causes in order to slow aging. Rejuvenation is the reversal of aging and thus requires a different strategy, namely repair of the damage that is associated with aging or replacement of damaged tissue with new tissue. Rejuvenation can be a means of life extension, but most life extension strategies do not involve rejuvenation. (Note the word: "hypothetical") Modern developments Aging is an accumulation of damage to macromolecules, cells, tissues and organs. If any of that damage can be repaired, the result is rejuvenation. There have been many experiments which have been shown to increase the maximum life span of laboratory animals, thereby achieving life extension. A few experimental methods such as replacing hormones to youthful levels have had considerable success in partially rejuvenating laboratory animals and humans. A recent experiment involved breeding genetically manipulated mice that lacked an enzyme called telomerase, causing the mice to age prematurely and suffer ailments. When the mice were given injections to reactivate the enzyme, it repaired the damaged tissues and reversed the signs of aging. There are at least eight important hormones that decline with age: 1. human growth hormone (HGH); 2. the sexual hormones: testosterone or estrogen/progesterone; 3. erythropoietin (EPO); 4. insulin; 5. DHEA; 6. melatonin; 7. thyroid; 8. pregnenolone. In theory, if all or some of these hormones are replaced, the body will respond to them as it did when it was younger, thus repairing and restoring many body functions. Most attempts at genetic repair have traditionally involved the use of a retrovirus to insert a new gene into a random position on a chromosome. But by attaching zinc fingers (which determine where transcription factors bind) to endonucleases (which break DNA strands), homologous recombination can be induced to correct and replace defective (or undesired) DNA sequences. The first applications of this technology are to isolate stem cells from the bone marrow of patients having blood diseasemutations, to correct those mutations in laboratory dishes using zinc finger endonucleases and to transplant the stem cells back into the patients. Stem cell Regenerative medicine uses three different strategies: Implantation of stem cells from culture into an existing tissue structure Implantation of stem cells into a tissue scaffold that guides restoration Induction of residual cells of a tissue structure to regenerate the necessary body part === === === Some of the old stories and myths of rejuvenation are very strange, and even horrific... Rock stars (like Mick Jagger) who have lived dissipated lives, have replaced their own blood, taking transfusions from others. THREE simple CORE STRATEGIES that I want to discuss here: On this thread, I want to focus on three main strategies: + Enhancing the NUTRIENTS and minerals that one consumes, + Eating less calories (& less toxic food), and + Making the intestines more alkaline, so as to improve the natural resistance to age-related diseases. : Rejuvenation Through Detoxification - Stephen Holt, MD, Ph http://www.youtube.com/watch?v=SzAJHV_-prA Link to comment Share on other sites More sharing options...
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